Detalhe da pesquisa
1.
γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A.
Mol Cell
; 76(6): 857-871.e9, 2019 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31586547
2.
The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells.
Mol Cell
; 69(6): 923-937.e8, 2018 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29547721
3.
Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth.
Mol Cell
; 64(5): 859-874, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27867011
4.
Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling.
Mol Cell
; 59(3): 345-358, 2015 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26145173
5.
Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth.
Mol Cell
; 55(4): 552-65, 2014 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25042803
6.
Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth.
Mol Cell
; 51(4): 506-518, 2013 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23932781
7.
Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.
Mol Cell
; 42(6): 719-30, 2011 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21700219
8.
HMG-CoA synthase 1 is a synthetic lethal partner of BRAFV600E in human cancers.
J Biol Chem
; 292(24): 10142-10152, 2017 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28468827
9.
Tyr-301 phosphorylation inhibits pyruvate dehydrogenase by blocking substrate binding and promotes the Warburg effect.
J Biol Chem
; 289(38): 26533-26541, 2014 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25104357
10.
DNA damage repair gene mutations predict the efficacy of platinum-based chemotherapy and immunotherapy plus platinum-based chemotherapy in advanced non-small cell lung cancer: a retrospective Chinese cohort study.
Transl Lung Cancer Res
; 11(12): 2539-2566, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36636408
11.
Efficacy of treatment for acneiform eruptions related to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) for non-small cell lung cancer (NSCLC): A protocol of systematic review and network meta-analysis.
Medicine (Baltimore)
; 100(1): e23875, 2021 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33429746
12.
Efficacy of Osimertinib in NSCLC Harboring Uncommon EGFR L861Q and Concurrent Mutations: Case Report and Literature Review.
Front Oncol
; 11: 731572, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34540698
13.
Network pharmacology based research into the effect and mechanism of Yinchenhao Decoction against Cholangiocarcinoma.
Chin Med
; 16(1): 13, 2021 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33478536
14.
High Glucose Activated Cardiac Fibroblasts by a Disruption of Mitochondria-Associated Membranes.
Front Physiol
; 12: 724470, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34483973
15.
Chinese herbal medicine for epidermal growth factor receptor inhibitor-induced skin rash in patients with malignancy: An updated meta-analysis of 23 randomized controlled trials.
Complement Ther Med
; 47: 102167, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31780021
16.
Mutant and Wild-Type Isocitrate Dehydrogenase 1 Share Enhancing Mechanisms Involving Distinct Tyrosine Kinase Cascades in Cancer.
Cancer Discov
; 9(6): 756-777, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30862724
17.
MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation.
Cancer Cell
; 34(2): 315-330.e7, 2018 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30033091
18.
Prevention of Dietary-Fat-Fueled Ketogenesis Attenuates BRAF V600E Tumor Growth.
Cell Metab
; 25(2): 358-373, 2017 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28089569
19.
Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation.
Nat Chem
; 7(12): 968-79, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26587712
20.
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Nat Cell Biol
; 17(11): 1484-96, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26479318